Prime Editing Illustration

2025-06-14

Collaboration with Heran Getachew and Marcela Garita-Hernandez to design scientific figures to illustrate their publication:

Getachew, H et al. (2025) Advances and optimization strategies in prime editing of human pluripotent stem cells.

doi.org/10.1016/j.tibtech.2025.06.017

InkScape (Vector Graphics)

In terms of tools, I was using Inkscape to create a single large SVG file containing a separate canvas per figure that I would rasterize as high-resolution TIFF (all at once or individually).

Just below, you'll find some of the final figures I made (click to enlarge):

Fig.1 - Key components of prime editing:

Abbreviation: RT, reverse transcriptase. Figure produced in collaboration with 42Borgata. (Published in Trends in Biotechnology)

Fig.2 - Mechanism of prime editing:

Abbreviations: PAM, protospacer adjacent motif; PBS, primer-binding site; RTT, reverse transcription template; WT, wild type. Figure produced in collaboration with 42Borgata. (Published in Trends in Biotechnology)

Fig.3 - Prime editors:

Abbreviations: prime-editing guide RNA (pegRNA); RT, reverse transcriptase; sgRNA, single-guide RNA. Figure produced in collaboration with 42Borgata. (Published in Trends in Biotechnology)